About Alfred Geller

neural gene transfer and gene therapy

We were responsible for the first direct gene transfer into neurons using a virus vector, the first correction of an animal model of neurological disease by direct gene transfer, and we have pioneered a helper virus-free HSV-1 vector system. Recently, we have developed technology to deliver different genes into presynaptic and postsynaptic neurons connected by a specific type of synapse. We have...

We were responsible for the first direct gene transfer into neurons using a virus vector, the first correction of an animal model of neurological disease by direct gene transfer, and we have pioneered a helper virus-free HSV-1 vector system. Recently, we have developed technology to deliver different genes into presynaptic and postsynaptic neurons connected by a specific type of synapse. We have a record of developing novel gene therapy approaches to cognitive deficits and neurodegenerative diseases. Our basic science studies focus on visual object learning.